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SARMs Directory
SARMs Dosing Protocols: Browse Research Guides
Research-use references for selective androgen receptor modulators (SARMs), grouped by goal, evidence level, and safety context. Each guide separates what has been studied in people from what has only been tested in animals or cells. This page is educational and is not medical advice.
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A-Z SARMs Directory
Filter the SARMs research index by letter to review queued and published SARM guides.
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How to Use This SARMs Library
This library helps you compare SARMs research guides side by side. You can sort by the research goal people associate with each compound, by how much human evidence exists, and by how much planning and monitoring a research protocol involves.
The most important thing to know up front is that the evidence is uneven. A few SARMs have real human trial data. Most have only been tested in animals or cells. Each guide labels this clearly so you are not comparing a well-studied compound against one that has barely been tested.
What each guide covers
- Plain-English definition and common names
- How much human versus preclinical evidence exists
- Research-context cycle structure and typical planning notes
- Side effect and suppression considerations from the literature
- Current regulatory status with dates
- Source-backed references
Research-use context
SARMs are not dietary supplements and are not approved for casual performance or physique use. As of June 2026, no SARM is FDA-approved for human use. This page is an educational research reference and does not provide medical advice or tell anyone to take a compound.
Browse SARMs by Goal
These groups reflect the research goals people most often associate with each compound. The grouping is about search interest, not proof. Evidence labels show how strong the actual data is for each one.
Lean Mass and Strength Research
Compounds most often discussed for muscle gain and strength in research contexts. These tend to be the most suppressive, so research protocols usually include recovery planning.
- RAD-140 (Testolone)Published
Potent SARM — lean mass and strength research
Strong animal data and an early human oncology trial. Often described as one of the most potent SARMs, with notable suppression in research.
Early human trial plus preclinical data
- Ligandrol (LGD-4033)Coming soon
Well-studied SARM — lean mass research
Has Phase 1 human safety data. Reported to raise lean body mass in early trials, with more suppression than Ostarine.
Phase 1 human trial data
- RAD-150 (TLB-150)Coming soon
RAD-140 ester analog — lean mass research
A chemical relative of RAD-140 with very little published data. Most information comes from community reports rather than studies.
Minimal published data
- S-23Coming soon
High-binding SARM — strength research
First studied as a possible male contraceptive. Binds the androgen receptor strongly and is highly suppressive in animal research. No human trials.
Preclinical only (no human trials)
Cutting and Recomposition Research
Compounds people associate with muscle retention during fat loss or body recomposition research.
- Ostarine (MK-2866)Coming soon
Most studied SARM — recomposition research
Also called enobosarm. The most studied SARM in people, with Phase 2 and Phase 3 trial history and FDA Fast Track status for a cancer indication. Still investigational.
Phase 2-3 human trial data
- Andarine (S-4)Coming soon
Older SARM — cutting research
One of the earlier SARMs, often discussed for cutting. Studied mostly in animals. Some users report a temporary yellow tint to vision.
Mostly preclinical
Myostatin and Lesser-Studied Research
Compounds tied to newer mechanisms or that simply have very little research behind them. Evidence here is the thinnest in the library.
- YK-11Coming soon
Steroidal compound — myostatin research
Linked to myostatin and follistatin research. Tested only in cells and animals. There is debate over whether it is a true SARM.
Preclinical / in vitro only
- ACP-105Coming soon
Early-stage SARM — receptor research
An early-stage SARM with animal data only. No published human trials exist.
Preclinical only
- AC-262 (AC-262536)Coming soon
Partial agonist — receptor research
A partial androgen receptor agonist studied in animals and cells. Little human-relevant data is available.
Preclinical only
SARMs Comparison Guide
Use this table to compare common research goals, how strong the evidence is, and how much planning a research protocol usually involves. It does not list doses and does not recommend human use.
| Research Goal | Relevant Guide | Evidence Context | Planning Complexity |
|---|---|---|---|
| Recomposition research | Ostarine (MK-2866) | Phase 2-3 human data; most studied SARM | Lower suppression reported; still monitored |
| Lean mass research | Ligandrol (LGD-4033) | Phase 1 human safety data | Moderate-to-high suppression discussed |
| Lean mass and strength research | RAD-140 (Testolone) | Early human trial plus preclinical data | High suppression discussed; recovery planning common |
| Cutting research | Andarine (S-4) | Mostly preclinical | Vision side-effect reports noted in literature |
| Strength research | S-23 | Preclinical only; no human trials | High suppression in animal research |
| Myostatin research | YK-11 | Preclinical / in vitro only | Sparse data; plan cautiously |
| Lean mass research | RAD-150 (TLB-150) | Minimal published data | Evidence too thin to compare reliably |
| Receptor research | ACP-105 | Preclinical only | Limited human-relevant context |
| Receptor research | AC-262 (AC-262536) | Preclinical only | Limited human-relevant context |
Evidence labels summarize the published record, not safety. Preclinical means animal or cell data only. Nothing in this table implies a human-use recommendation.
Recently Added and Updated
These SARMs research guides are the newest additions to this directory.
- June 2026: Ostarine (MK-2866): New research guide planned; most human evidence of any SARM.
- June 2026: Ligandrol (LGD-4033): New research guide planned; Phase 1 human data summary.
- June 2026: RAD-140 (Testolone): Published research guide covering human trial context, liver-injury case reports, and regulatory status.
Every SARMs guide carries a visible last-reviewed date and is updated when evidence, safety context, or regulatory status changes.
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Request a guideFrequently Asked Questions: SARMs Dosing Protocols
Are SARMs dosing protocols medical advice?
No. This library is an educational research reference and is not medical advice. SARMs are not approved for human use. Talk to a licensed healthcare professional before making any health decision.
Are SARMs legal or FDA-approved?
As of June 2026, no SARM is approved by the FDA for human use. All SARMs are investigational research chemicals. The FDA has warned companies against selling them as dietary supplements, and a proposed SARMs Control Act has sought to classify several as Schedule III controlled substances. Laws differ by country and can change. See the FDA's SARMs warning.
Which SARM has the most human research?
Ostarine, also called enobosarm or MK-2866, has by far the most human data. It has been tested in Phase 2 and Phase 3 trials and received FDA Fast Track status for a breast cancer indication, though it is still not approved. LGD-4033 has Phase 1 data. Most other SARMs have only been tested in animals or cells.
What is the difference between SARMs and anabolic steroids?
SARMs are designed to act mainly on muscle and bone while having less effect on other tissues, which is the theory behind the word selective. In practice, many SARMs still lower natural testosterone and carry real risks, including liver and cholesterol changes reported in the research. The selectivity is a research goal, not a guarantee of safety.
Do SARMs cause testosterone suppression?
Many do. Compounds like RAD-140, LGD-4033, S-23, and andarine are described in the research as suppressive, while Ostarine is reported as milder. Suppression tends to be larger at higher doses and longer durations. Research discussions of recovery and post-cycle therapy reflect this, but this page does not provide a protocol.
Are SARMs banned in sports?
Yes. The World Anti-Doping Agency prohibits SARMs at all times, both in and out of competition. Athletes have tested positive across many sports. You can read more at USADA.
Which SARMs have little or no human data?
S-23, YK-11, ACP-105, AC-262, and RAD-150 have essentially no human trials. Andarine (S-4) is also mostly preclinical. For these, claims about results come from animal studies or community reports, not controlled human research.
How is this SARMs library organized?
Guides are listed A-Z in the directory and grouped by goal, such as lean mass research, cutting research, and lesser-studied compounds. Each guide also shows an evidence label so you can quickly see how much human data exists.